July 29th, 2015

Researchers from Shahid Beheshti University in Iran produced and studied a non-enzyme biosensor sample to obtain a quick method to detect the level of blood sugar in diabetic patients.

The sensor has high sensitivity and accuracy and can easily determine the amount of glucose in the presence of disturbing species.
In this research, a sample of non-enzyme electrochemical biosensor was produced and studied. The surface of the electrode used in the structure of the sensor was modified with a nanocomposite containing carbon nanotubes and conductive polymer which has gold nanoparticles.
Enzyme electrochemical sensors have high selectivity and sensitivity due to the activity of the enzyme. However, there are limitations in the application of these sensors, including the dependency of enzyme response to temperature, chemical instability and expensive price. Therefore, new researches have lately been carried out on the designing of non-enzyme sensors based on modified electrodes. In this group of biosensors, the sensitivity and selectivity highly depend on the electrochemical activity of the electrode modifiers.
Results of the research showed that the nanocomposite used for the modification of the sensor surface has desirable electrochemical activity and repeatability for the oxidation of glucose. In addition, the electrode modified with the nanocomposite is not sensitive to the disturbing species that exist in blood sample. This parameter is considered a huge advantage in biosensors. Among other characteristics of the sensor, mention can be made of high sensitivity, reusability and wide range of linear response.